The Emergence Diet : Get Out of Torpor!

In this video I ask how mammals get out of torpor.

Grizzly bears are the most appropriate model organism: monogastric, large-bodied, omnivorous hibernators. We also happen to have very detailed knowledge about their diet and it may not be what you think.

Before that, I look at the argument that you really ARE in torpor, how you got there and ways to determine whether you are.

Signs that you might be in torpor include low Vitamin B6, high kynurenine, high homocysteine, high nicotinamide and high 4-HNE (Ox-LDL).

Things hibernators use to get OUT of torpor (Emergence): 1) oxidants like succinate, alpha-ketoglutarate and pyruvate. These help inject oxygen so that you can burn fat. 2) Methyl groups in the form of SAMe. You could also use betaine, choline, methyl folate. 3) Dietary folate, B12, and polyphenols. All of these things help to limit Aryl Hydrocarbon Receptor activity. 4) Cholesterol excretagogues such as dandelions. You could use Pu-Ehr tea extract. 5) Bitter flavors such as dandelions. These activate bitter taste receptors and release GLP-1, the active ingredient in popular weight loss drugs like semaglutide.

Things hibernators use to get INTO torpor (Immergence): 1) Dietary MUFA. Often in the form of insects. 2) Dietary PUFA. Often in the form of nuts/acorns. The grizzly bears in Yellostone use pine nuts. 3) Dietary fructose. From fruit. 4) Lack of folate/B12/polyphenols.

3 thoughts on “The Emergence Diet : Get Out of Torpor!”

  1. Brad I love your videos and strong scientific presentation. I can’t add much as I am still learning from you. But what I can say is that humans are at their best on a traditional diet as are the other species… Shannon !

  2. Hey Brad,

    i’m trying to save money by cutting supplements out if my life. Do you think a person can get out of torpor just by drinking Pu’erh Tea, avoiding PUFA like the plague, adding bitter herbs to the diet and eating foods that are high in folate, B6 and B12?

    Or do the supplements you reccomended do most of the heavy lifting in that area?

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