At the beginning of this series I stated that any theory of obesity should be able to explain why a […]

Satiation is a feeling that is actually triggered in the brain by specific neurons in the hypothalamus. These neurons respond […]

This paper measured the level of Stearoyl-CoA desaturase in morbidly obese adults compared to adults with a normal BMI. The […]

A “knockout mouse” is a strain of mice in which a section of their DNA has been deleted. Therefore, they […]

When fat cells respond to insulin they take several actions in switching from fat burning mode to glucose burning and […]

If you’ve been reading along you know that by this point we’ve shown that long chain saturated fat consumption causes […]

In this series we’ve discussed the fact that saturated fat oxidation leads to ROS production in the mitochondria which makes […]

In previous posts I have laid out the argument that metabolism of long chain saturated fat creates mitochondrial ROS which […]

In this series I often mention that mitochondrial ROS production creates physiological insulin resistance which keeps your cells in “fat […]

Let’s think about what happens in response to a starchy meal. Blood sugar rises and insulin is released. Insulin attaches […]

In the introductory series, we first saw an example of ROS (Reactive Oxygen Species) as a signal in a small […]