The SCD1 Theory Of Obesity

New List of Additional SCD1 Regulators posted at r/SaturatedFat

There is a great discussion thread for Croissant Diet/ROS Theory of Obesity/SCD1 Theory of Obesity over on reddit. u/Magnum2684 posted a list of additional things that can affect SCD1 levels. It’s a bit confusing to me – when they say “positive” they mean “reduces SCD1 expression” and when they say “negative” they mean “increases SCD1 …

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Dietary Monounsaturated Fat, The SCD1 Theory of Obesity, Part 3

Introduction This is the third part of my SCD1 Theory of Obesity series.  Here are part 1 and part 2.  There is a brief synopsis of the theory below if you don’t want to start from the beginning. Since I published the ROS theory of obesity, one of the most common questions I’ve gotten is, …

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The SCD1 Theory of Obesity Part 2 – The Post Obese Metabolism and What You Can Do About It

AKA The Ros Theory of Obesity Part2, Part 2 Introduction In part 1, I explained that SCD1 is up-regulated in things that are fat and that in fact up-regulating SCD1 in something is sufficient to make it store fat.  Insulin is trying to upregulate SCD1 while leptin down-regulates it.  The mechanism by which leptin down-regulates …

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The SCD1 Theory of Obesity, Part 1 – Insulin, Leptin, SCD1 and Thermogenesis

AKA The ROS Theory of Obesity Part 2, Part 1 Introduction In The ROS Theory Of Obesity, I argued that the key determinant of body fatness was the saturation level of fat as it enters the mitochondria.  In The Croissant Diet I addressed the dietary half of this equation, arguing that to lose weight you …

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