Intro To Oxidation

Introduction to Fire In a Bottle

Save Thirty Bucks on Low-PUFA Pork! Pork without seed oils.

Over at Firebrand Meats I sell heirloom berkshire pork that has been raised on a diet that is low in PUFA. Animals cannot make polyunsaturated fat, so if you limit what’s in their diet, you can lower the amount that is in the meat. I summarized the problems with PUFA in pork and poultry in …

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Oxidized Seed Oils Cause Diabetes

This paper from Finland is literally the greatest nutrition paper I’ve ever seen. (Lankinen, 2019) It’s long been known that high plasma levels of linoleic acid predict low diabetes risk. (Kroger, 2010) Furthermore, plasma levels of linoleic acid are a biomarker for intake. At this point people of a certain predisposition will say, “See! I …

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Reductive stress is the POTENTIAL for oxidative stress

Is it lazy to just post my own tweet and call it an article? You decide. Reducive stress(RS) vs Oxidative stress (OS): they are not opposites, RS is the POTENTIAL for OS. Reduced things (NADH, NADPH, GSH) are electron donors. If they give those electrons to O2 it makes superoxide (O2-). You can't make O2- …

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Reductive Stress Causes Oxidative Stress: Antioxidants, Oxidative Stress and Reductive Stress

Introduction This is the second article in my series about reductive stress. Check out the intro. The terms oxidative stress and antioxidant have been thrown around a lot in recent decades, often without a clear understanding of their true nature.  Oxidative stress is caused by an overproduction of superoxide and hydrogen peroxide or by a …

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David Rosenberg increased his metabolic rate by 1100 calories per day with alpha-lipoic acid, succinade, sterculia oil and stearic acid.

I was excited when David reached out to me because he is very regimented. He has literally weighed and recorded the macros of every piece of food he has eaten going back to July of 2021. He exercises the same amount each week, the same number of reps of the same exercises. When he jogs …

David Rosenberg increased his metabolic rate by 1100 calories per day with alpha-lipoic acid, succinade, sterculia oil and stearic acid. Read More »

FIAB Podcast, Episode 4: Reductive Stress

A Google Scholar search for the phrase “oxidative stress diabetes” currently yields over 500,000 papers, but the phrase “reductive stress diabetes” yields only 17,000, a discrepancy of 30 to 1. I believe the underlying issue at the heart of our metabolic woes is reductive stress, which looks to cells like too much cellular energy. In …

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NAD+, Reductive Stress and the Magic of Superoxide

This is the next in a series of posts I am writing about reductive stress as defined by the NAD+/NADH.  This post looks at the uniqueness of superoxide as a reduced electron carrier.  Superoxide is not like the other electron carriers.  Most electron carriers, such as NADH, need to give their electron to something else …

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Lactate and the Lipoic Acid Flu, An Hypothesis and n=1

In my last post I recommended a strategy of combining lipoic acid – a natural, mitochondrially produced substance which oxidizes NADH to NAD+ – and succinate, which drives mitochondrial ROS production and oxidation of NADH to NAD+ via the activity of the enzyme NNT. Both of these are designed to shift the redox pool of …

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