People talk about calories-in, calories-out. It is the idea that weight will be gained if you eat extra calories or lost if you burn extra calories, say by exercising.
Many studies have been done and calorie restriction or exercise for weight loss and the results are very: these are losing strategies.
In this video I take a look at why tracking electrons is much more useful than tracking calories. These mice got fat. Not because they were lazy, not be cause they overate. They got fat because they lost the mechanism that creates electrons out.
Li, Y., Mouche, S., Sajic, T., Veyrat-Durebex, C., Supale, R., Pierroz, D., Ferrari, S., Negro, F., Hasler, U., Feraille, E., Moll, S., Meda, P., Deffert, C., Montet, X., Krause, K.-H., & Szanto, I. (2012). Deficiency in the NADPH oxidase 4 predisposes towards diet-induced obesity. In International Journal of Obesity (Vol. 36, Issue 12, pp. 1503–1513). Springer Science and Business Media LLC. https://doi.org/10.1038/ijo.2011.279