As a biologist, I always think in evolutionary terms. All mammals share a single ancestor who had developed a warm-blooded metabolism. Many mammals hibernate: bears, ground squirrels, skunks, bats, anteaters, etc. To hibernate, you have to throttle back your warm-blooded metabolism to a torpid one allowing your metabolic rate and body temperature to drop. Since …
Recently I posted an article recommending combining sterculia oil with berberine and/or fish oil as a way to escape torpor. I chose this combination because they mimic the effects of leptin, the hormone produced by our fat cells whose job is to keep us lean but to which most of us are resistant. As discussed …
n=1 on Escaping Torpor: Turning off PPAR gamma and turning on Fat Burning Read More »
Introduction If you follow this blog you probably won’t be SHOCKED that I’m following up Metabolic Rates in American Women Plunged Between 1919 and 1986 with this post. The same group that did the 1986 paper about metabolic rates in women followed it up with a paper about men in 1987.1 They conclude, “The classic …
Metabolic Rates In American Men Plunged Between 1919 and 1987 Read More »
Intro I have suggested that increased consumption of the Omega 6 polyunsatured fat (PUFA) linoleic acid throughout the 20th century has led to an American population where the majority of us are in a torpor-like state as defined by high levels of stored PUFA in our bodyfat coupled with high expression of the transcription factor …
Metabolic Rates in American Women Plunged Between 1919 and 1986 Read More »
Brad’s Daily Recipe Introduction I’d like to reach my target weight this year or next, but more importantly I’d like to understand HOW I get there as the journey continues. I’m not interested in losing weight by starving myself, I’d like to FIX my metabolism. Many (most?) of us are in a torpor-like state as …
Inroduction So I have a fancy metabolic tester to track my metabolic rate. It’s honestly pretty amazing if you have $7500 burning a hole on your pocket. Sometimes they have deals and I’m an affiliate so if you give them my code “BMarsh”, you’ll get $600 off. If you can’t afford a metabolic tester, here’s …
Study Design I started my sterculia oil (SO) trial with a 16 week n=1 safety trial. I took a lot of the oil – 4400 mg which is 1 tsp daily – for 8 weeks. I would NOT take this much but I wanted to make sure it was safe. Then I didn’t take any …
Introduction It’s time for the season finale! Next week I will pivot to discussing my personal results of using sterculia oil to inhibit SCD1. In this post I will summarize my posts on the topic to date before bringing the thread to a near term conclusion using an example that in retrospect will be so …
Are You In Deep Torpor? SCD1 Theory Of Obesity Summary So Far And Hamsters! Read More »
Overview Very Long Chain Fatty Acids (VLCFA) I’ve become very interested in very long chain fats – those weird ones that you ignored on your OmegaQuant test. Things like behenic acid, a 22 carbon length saturated fat. In Good PPAR, Bad PPAR, I pointed out that there is a positive feedback loop where too much …
Very Long Chain Saturated and Monounsaturated Fats Read More »
I’ve been promoting the OmagaQuant complete test as a way to calculate your Desaturase Indix (DI or DI18) to know your SCD1 levels. This is calculated by dividing your oleic acid (18:1) by your stearic acid (18:0). There are a lot of questions about what people’s numbers SHOULD look like. Ideally your DI should be …
Membrane Phospholipid Composition of Different Populations Read More »
Overview Introduction I introduced PPAR alpha in Dietary Monounsaturated Fat as an altogether good actor, doing things like increasing the rate of fat burning. The PPAR genes are indeed master metabolic regulators. In this post I’m going to introduce PPAR alpha’s troubled sibling, PPAR gamma. The PPARs are transcription factors, which is to say that …
Introduction The most common explanation given for the recent wave of obesity is that “We don’t work as hard as we used to and we overeat.” This is what evolutionary biologist Stephen Jay Gould calls a “just-so story”, an untestable narrative explanation for a cultural practice, a biological trait, or behavior of humans or other …
This is a pretty great testimonial to the potential of The Croissant Diet. David really took this principle seriously, eating croissants with butter and cheese, cheseburgers and Haagen-Das. He did a great job of collecting data during his journey, including before and after photos. Some days he consumed close to 5000 calories! Detailed reports of …
This was posted by a user of the reddit group r/SaturatedFat. This is a great forum for discussing issues relevant to Fire In A Bottle, Hyperlipid, SCD1, etc. This post is particularly interesting – Dr. Ntambi did much of the early research on SCD1. You can hear his thoughts and findings about it at the …
Really Good Historical Video About The History of SCD1 research Posted at r/SaturatedFat Read More »
Introduction This is a followup to my post Native Americans Removed Acorn Oil and Replaced It With Bear Fat. It also carries on the theme of adaptive thermogensis, which I introduced in This is Your Body Temperature on Vegetable Oil and continued in The Body Fat Saturation Of Starch Eaters; Linoleic Acid Dysregulates SCD1. In …
Bear Hunting Season; Native Americans Hunted Bear When The PUFA Content Was Lowest Read More »
