Overview Introduction I introduced PPAR alpha in Dietary Monounsaturated Fat as an altogether good actor, doing things like increasing the rate of fat burning. The PPAR genes are indeed master metabolic regulators. In this post I’m going to introduce PPAR alpha’s troubled sibling, PPAR gamma. The PPARs are transcription factors, which is to say that …
Introduction The most common explanation given for the recent wave of obesity is that “We don’t work as hard as we used to and we overeat.” This is what evolutionary biologist Stephen Jay Gould calls a “just-so story”, an untestable narrative explanation for a cultural practice, a biological trait, or behavior of humans or other …
This is a pretty great testimonial to the potential of The Croissant Diet. David really took this principle seriously, eating croissants with butter and cheese, cheseburgers and Haagen-Das. He did a great job of collecting data during his journey, including before and after photos. Some days he consumed close to 5000 calories! Detailed reports of …
This was posted by a user of the reddit group r/SaturatedFat. This is a great forum for discussing issues relevant to Fire In A Bottle, Hyperlipid, SCD1, etc. This post is particularly interesting – Dr. Ntambi did much of the early research on SCD1. You can hear his thoughts and findings about it at the …
Really Good Historical Video About The History of SCD1 research Posted at r/SaturatedFat Read More »
Introduction This is a followup to my post Native Americans Removed Acorn Oil and Replaced It With Bear Fat. It also carries on the theme of adaptive thermogensis, which I introduced in This is Your Body Temperature on Vegetable Oil and continued in The Body Fat Saturation Of Starch Eaters; Linoleic Acid Dysregulates SCD1. In …
Bear Hunting Season; Native Americans Hunted Bear When The PUFA Content Was Lowest Read More »
Lori reached out to me wanting to share her story. She initially sent me this email: First of all, thank you!I’ve been doing TCD since your first post.I’m a 63 year old female who is kind of dietary lazy.I didn’t count macros or calories or anything else. For about a year, I had one rule.No …
I’ve argued in The SCD1 Theory of Obesity Part One and Part Two, as well as in This Is Your Body Temperature On Vegetable Oil that if your body fat is highly saturated, you will respond to an increase in body fat by increasing your metabolic rate through a process known as adaptive thermogenesis. In …
The Body Fat Saturation Of Starch Eaters; Linoleic Acid Dysregulates SCD1 Read More »
Introduction In a previous article, I argued that a recent drop in the body temperatures of the Tsimane people of Bolivia was caused by the introduction of vegetable oil to a mostly starch diet. Native Americans used acorns as a staple starch, but they removed the oil form them before eating. However, they often added …
Native Americans Removed Acorn Oil and Replaced It With Bear Fat Read More »
They really let anyone on podcasts these days! Listen to Brad join obesity clinic doctors on Low Carb MD. They talk about the theories behind The Croissant Diet with a doctor who is in a clinic working with people fighting obesity every day. So it’s a little more of a hands on clinical perspective than in other podcasts we’ve done, and …
It’s rare to find a scientific paper whose RESULTS are hilarious. Sometimes the authors conclusions are hilarious. If you’ve lived through the last 30 years of articles about the best sources of antioxidants and how to avoid oxidative stress, though, the actual findings of this study​1​ will certainly seem ironic, if not hilarious. I’ve written …
Speed Your Metabolism With Oxidative Stress! Slow It With Antioxidants! Read More »
Introduction This article suggests that the reason the Tsimane people of Bolivia experienced a significant, well-documented drop in their body temperature and metabolic rate over the past 15 years is that their fat became less saturated due to newly available “store bought foods”, most of which are loaded with polyunsaturated fat (PUFA). This drop in …
World premiere SCD1 podcast!
There is a great discussion thread for Croissant Diet/ROS Theory of Obesity/SCD1 Theory of Obesity over on reddit. u/Magnum2684 posted a list of additional things that can affect SCD1 levels. It’s a bit confusing to me – when they say “positive” they mean “reduces SCD1 expression” and when they say “negative” they mean “increases SCD1 …
New List of Additional SCD1 Regulators posted at r/SaturatedFat Read More »
Katie sent me this paper.​1​ It actually adds an interesting twist to her story that I already published. She reached out to me last week with her Desaturase Index test results. The test is here. Her score was around a 1.6, which is relatively good and significantly better than where I started out at 2.1. …
Introduction This is the third part of my SCD1 Theory of Obesity series. Here are part 1 and part 2. There is a brief synopsis of the theory below if you don’t want to start from the beginning. Since I published the ROS theory of obesity, one of the most common questions I’ve gotten is, …
Dietary Monounsaturated Fat, The SCD1 Theory of Obesity, Part 3 Read More »
