New List of Additional SCD1 Regulators posted at r/SaturatedFat

There is a great discussion thread for Croissant Diet/ROS Theory of Obesity/SCD1 Theory of Obesity over on reddit. u/Magnum2684 posted a list of additional things that can affect SCD1 levels. It’s a bit confusing to me – when they say “positive” they mean “reduces SCD1 expression” and when they say “negative” they mean “increases SCD1 …

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Pu’erh Tea is a potent Suppressor of SCD1

Katie sent me this paper.​1​ It actually adds an interesting twist to her story that I already published. She reached out to me last week with her Desaturase Index test results. The test is here. Her score was around a 1.6, which is relatively good and significantly better than where I started out at 2.1. …

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Dietary Monounsaturated Fat, The SCD1 Theory of Obesity, Part 3

Introduction This is the third part of my SCD1 Theory of Obesity series.  Here are part 1 and part 2.  There is a brief synopsis of the theory below if you don’t want to start from the beginning. Since I published the ROS theory of obesity, one of the most common questions I’ve gotten is, …

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The SCD1 Theory of Obesity Part 2 – The Post Obese Metabolism and What You Can Do About It

AKA The Ros Theory of Obesity Part2, Part 2 Introduction In part 1, I explained that SCD1 is up-regulated in things that are fat and that in fact up-regulating SCD1 in something is sufficient to make it store fat.  Insulin is trying to upregulate SCD1 while leptin down-regulates it.  The mechanism by which leptin down-regulates …

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The SCD1 Theory of Obesity, Part 1 – Insulin, Leptin, SCD1 and Thermogenesis

AKA The ROS Theory of Obesity Part 2, Part 1 Introduction In The ROS Theory Of Obesity, I argued that the key determinant of body fatness was the saturation level of fat as it enters the mitochondria.  In The Croissant Diet I addressed the dietary half of this equation, arguing that to lose weight you …

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Brad’s Inflammation Blood Test Numbers – Don’t Conflate Inflammation and ROS!

So I do everything wrong, kind of on purpose. I eat white flour and dairy. I combine starch, protein and saturated fat. I drink black coffee and/or red wine all day long. MANY/MOST OF MY MEALS ARE DEEP FRIED. My sleep habits are haphazard at best. This is the time of year when they are …

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Kirsten’s TCD Post

Kirsten Mortenson, a novelist, posted a nice writeup of her experience with TCD after almost a year. Here’s a preview. Read the full post at kirstenmortensen.com. She also has some pretty good looking novels for sale!

Podcasts!

I’ve had a busy summer of recording podcasts! There are hours of me blathering on now. 😉 I’ll list them here starting with the most recent. Low Carb MD. Listen to Brad join obesity clinic doctors on Low Carb MD. They talk about the theories behind The Croissant Diet with a doctor who is in a clinic working with people …

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Katie’s Story

Katie is doing a textbook version of TCD. I love her story, it’s honest and real. She also shares in the joy of realization that if you choose the right fats, food becomes something to be enjoyed again! Here is her story, verbatim as she sent it to me. I’m Katie, a 6 foot tall, …

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James’ Story

James posted his success with TCD on Reddit. I reached out to see if he wanted to share and he obliged. James is doing TCD to the tee: using starches to absorb highly saturated fats. He has experienced many of the same benefits I originally described in Introducing The Croissant Diet: increased satiation, increased energy, …

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Butter May Lower LPS Mediated Inflammation Compared to Olive Oil

While recording a podcast with Ben Greenfield, I was discussing how the French, Tibetan yak herders and early American farmers all had a diet combining saturated fat (butter) with starch yet appeared to stay lean and healthy. Ben then suggested that there were studies showing that combining saturated fat with starch increases LPS. LPS is …

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